Skip to main content

Table 1 Expansion of protein families with innate immunity domains in amphioxus

From: Novel genes dramatically alter regulatory network topology in amphioxus

Genome

TIR

NACHT

Homo sapiens (human)

24 (23)

23 (22)

Mus musculus (mouse)

24 (22)

33 (33)

Canis familiaris (dog)

26 (25)

17 (17)

Gallus gallus (chicken)

28 (27)

6 (6)

Xenopus tropicalis (western clawed frog)

28 (28)

22 (21)

Danio rerio (zebrafish)

30 (29)

21 (19)

Fugu rubripes (Japanese pufferfish)

17 (16)

180 (116)

Tetraodon nigroviridis (green pufferfish)

23 (20)

80 (11)

Ciona intestinalis (transparent sea squirt)

4 (4)

49 (45)

Branchiostoma floridae (amphioxus)

134 (125)

95 (94)

Strongylocentrotus purpuratus (purple sea urchin)

244 (216)

326 (320)

Drosophila melanogaster (fruit fly)

11 (11)

0

Caenorhabdidits elegans

2 (2)

0

Nematostella vectensis (sea anemone)

7 (7)

45 (43)

  1. The value in each domain category for each species is the total number of full-length protein sequence hits, with the number confirmed by Pfam Protein Search or NCBI CD-Search under the default threshold shown in parentheses. Because of the extreme diversity of both TIR and NACHT domains and experimental verification of only limited numbers of gene predictions, the numbers of predicted proteins in all recently sequenced genomes are considered as approximations, dependent on significance thresholds for gene predictions and specific homology recognition tools used in the analysis. For a detailed list of protein sequences, see Additional data files 1 and 2.