Table 3 Common genes significantly increased in glaucomatous ONH astrocytes compared to their normal counterparts
| Â | Â | Â | AAG-AA (U133Av2) | CAG-CA (U95Av2) | ||
|---|---|---|---|---|---|---|
Symbol | Description | CL | FC | p-value | FC | p-value |
ABCA8 | ATP-binding cassette, sub-family A, member 8 | 17q24 | 2.34 | 0.0291 | 2.53 | 9.43E-05 |
C5orf30 | Chromosome 5 open reading frame 30 | 5q21.1 | 1.57 | 0.0028 | 1.48 | 0.0042 |
CASK | Calcium/calmodulin-dependent serine protein kinase | Xp11.4 | 1.99 | 0.0064 | 1.31 | 0.002 |
CASP4 | Caspase 4, apoptosis-related cysteine peptidase | 11q22.2-q22.3 | 1.59 | 0.0007 | 1.9 | 0.0026 |
GSTA4 | Glutathione S-transferase A4 | 6p12.1 | 1.25 | 0.005 | 1.85 | 5.21E-05 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 2q32.3-q33 | 1.89 | 0.0023 | 1.38 | 0.0075 |
HEPH | Hephaestin | Xq11-q12 | 4.15 | 0.0021 | 1.88 | 0.0021 |
HOXB2 | Homeobox B2 | 17q21-q22 | 1.59 | 0.0133 | 1.86 | 0.0014 |
KCNK2 | Potassium channel, subfamily K, member 2 | 1q41 | 1.55 | 0.0489 | 1.52 | 0.0024 |
KIAA1199 | KIAA1199 | 15q24 | 1.68 | 0.0152 | 1.94 | 0.0026 |
LMO4 | LIM domain only 4 | 1p22.3 | 1.7 | 0.0034 | 1.83 | 0.0052 |
MYH10 | Myosin, heavy polypeptide 10, non-muscle | 17p13 | 1.64 | 0.0012 | 1.57 | 0.0017 |
PYGL | Phosphorylase, glycogen; liver | 14q21-q22 | 1.47 | 0.0141 | 2.2 | 0.0025 |
RBP1 | Retinol binding protein 1, cellular | 3q23 | 2.2 | 0.0007 | 2.32 | 0.00073 |
SERPING1 | Serpin peptidase inhibitor, clade G, member 1 | 11q12-q13.1 | 2.3 | 0.0064 | 1.86 | 0.0014 |
SH3BP5 | SH3-domain binding protein 5 | 3p24.3 | 1.65 | 0.0407 | 2.74 | 4.87E-05 |
SLIT2 | Slit homolog 2 | 4p15.2 | 1.6 | 0.0077 | 1.42 | 0.0027 |
TINP1 | TGF beta-inducible nuclear protein 1 | 5q13.3 | 1.53 | 7.93E-05 | 1.36 | 0.0055 |