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Table 2 Statistics for ChIP tag differences in the two copies of human SDs

From: Asymmetric histone modifications between the original and derived loci of human segmental duplications

 

All SDs (n = 25,914)

Post-macaque SDs (n = 1,646)

Factors

Paired t-test p-values

Wilcoxon signed rank test p-values

Mean of parental

Standard deviation of parental

Mean of derivative

Standard deviation of derivative

Paired t-test p-values

Mean of difference

Wilcoxon signed rank test p-values

H2AZ

3.64E-05

2.86E-07

1.319

2.388

1.114

1.987

5.51E-03

0.205

1.58E-03

H2BK5me1

2.92E-01

2.32E-02

2.600

6.582

1.224

3.237

1.49E-15

1.377

2.20E-16

H3K27me1

2.12E-05

5.92E-03

2.147

2.415

1.250

1.786

2.20E-16

0.897

2.20E-16

H3K27me2

9.71E-10

1.74E-11

1.526

1.670

1.355

1.668

5.60E-04

0.170

5.08E-05

H3K27me3

2.20E-16

4.60E-14

1.492

1.727

1.460

2.003

6.09E-01

0.031

2.95E-01

H3K36me1

1.48E-05

2.28E-10

1.533

1.392

1.242

1.638

8.66E-10

0.291

2.20E-16

H3K36me3

1.29E-02

1.57E-05

3.755

6.347

1.796

3.027

2.20E-16

1.959

2.20E-16

H3K4me1

3.63E-01

8.01E-03

2.700

6.895

1.139

2.741

2.20E-16

1.562

2.20E-16

H3K4me2

8.76E-01

9.66E-06

1.354

2.290

0.651

1.458

2.20E-16

0.703

2.20E-16

H3K4me3

6.68E-01

7.46E-11

4.144

16.473

1.987

6.256

7.06E-07

2.157

4.44E-16

H3K79me1

6.49E-12

2.20E-16

1.911

1.644

1.484

1.781

2.20E-16

0.427

2.20E-16

H3K79me2

3.12E-02

1.26E-02

0.476

0.520

0.356

0.499

1.94E-08

0.120

3.45E-11

H3K79me3

9.62E-04

2.06E-06

1.823

2.595

1.671

2.941

5.76E-02

0.153

3.76E-05

H3K9me1

2.42E-02

6.41E-04

2.262

3.827

1.046

2.171

2.20E-16

1.215

2.20E-16

H3K9me2

1.67E-07

3.73E-14

1.618

1.865

1.489

1.936

1.88E-02

0.130

5.80E-03

H3K9me3

2.40E-03

3.90E-06

1.380

2.323

1.357

2.357

7.25E-01

0.023

3.61E-01

H3R2me1

2.19E-05

4.41E-09

1.878

1.751

1.440

1.866

2.20E-16

0.438

2.20E-16

H3R2me2

4.60E-01

4.41E-01

1.292

1.263

1.079

1.500

1.40E-06

0.213

1.18E-11

H4K20me1

5.72E-04

6.77E-05

4.865

18.476

1.257

5.664

9.85E-13

3.608

2.20E-16

H4K20me3

3.23E-01

5.78E-01

1.687

6.408

1.953

5.677

1.26E-01

-0.266

2.03E-01

H4R3me2

2.16E-01

5.43E-01

1.439

1.404

1.165

1.666

1.91E-10

0.275

6.66E-16

Pol II

4.24E-01

2.45E-04

1.538

4.476

0.507

0.812

6.47E-16

1.031

2.20E-16

CTCF

9.31E-02

6.45E-05

0.757

1.560

0.521

1.226

1.41E-06

0.236

2.20E-16

H3K4me3, ES

0.0008

0.294

5.673

9.20

1.423

4.89

2.30E-06

4.25

1.91E-10

H3K27me3, ES

0.0024

7.63E-06

2.203

3.255

1.958

3.314

0.71

0.245

0.534

  1. The p-values are before adjustment for multiple testing; statistically significant results (by t-test) are in bold.