Table 1 Summary of genes implicated in gastric function in platypus
From: Loss of genes implicated in gastric function during platypus evolution
Protein | Gene | Status in platypus genome | Confirmatory evidence |
|---|---|---|---|
ATPase, H+/K+ exchanging, α polypeptide | ATP4A | Absent | Southern blot |
ATPase, H+/K+ exchanging, β polypeptide | ATP4B | Pseudogene | PCR/direct sequencing |
Cathepsin E | CTSE | Pseudogene | PCR/direct sequencing |
Gastrin | GAST | Absent | Southern blot |
Neurogenin 3 | NGN3 | Absent | Southern blot |
Pepsin A | PGA | Absent | Southern blot/sequencing |
Pepsin C | PGC | Absent | Southern blot/sequencing |
Gastric intrinsic factor | GIF | Present (expression pancreatic) | RT-PCR |
Chymosin | CYMP | Present (expression not detected) | Sequencing/RT-PCR |