Table 2 Aging-associated probe sets that are differentially expressed in wounds from elderly compared to young subjects
From: Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly
Affy ID | Gene* | Gene (description) | Function | q-value†| FC‡ |
|---|---|---|---|---|---|
Down-regulated probe sets (12) | Â | Â | Â | Â | Â |
   217496_s_at | IDE § | insulin-degrading enzyme | Wound fluid/resolution of insulin response | 4.0E-06 | -20.5 |
   210074_at | CTSL2 § | cathepsin L2 | Lysosomal cysteine proteinase | 3.8E-05 | -15.5 |
   214131_at | SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 | UV-responsive proteinase inhibitor | 1.1E-03 | -15.0 |
   214131_at | C12orf5 | chromosome 12 open reading frame 5 | Protection from DNA damage | 1.1E-03 | -12.8 |
   204733_at | KLK6 § | kallikrein 6 (neurosin, zyme) | Hormone regulated serine protease | 1.4E-05 | -11.9 |
   202179_at | BLMH § | bleomycin hydrolase | Alzheimer's-associated cysteine peptidase | 2.1E-03 | -11.8 |
   210338_s_at | HSPA8 § | heat shock 70 kDa protein 8 | Aging-associated heat shock protein | 9.9E-04 | -10.6 |
   201849_at | BNIP3 § | BCL2/adenovirus E1B 19 kDa interacting protein 3 | Mitochondrial apoptosis-inducing | 2.7E-04 | -10.1 |
   203328_x_at | IDE § | insulin-degrading enzyme | Wound fluid/resolution of insulin response | 1.4E-05 | -17.4 |
   203327_at | IDE § | insulin-degrading enzyme | Wound fluid/resolution of insulin response | 7.0E-04 | -9.3 |
   205016_at | TGFA § | transforming growth factor, alpha | IFN-induced/epidermal regeneration | 1.0E-03 | -8.5 |
   212907_at | SLC30A1 | Solute carrier family 30 (zinc transporter), member 1 | Zinc/calcium ion transporter | 8.5E-04 | -7.3 |