Table 3 Putative and known antimicrobial drug and heavy metal resistance genes in the S. maltophilia K279a genome sequence
Substrate | Gene | Putative gene product |
|---|---|---|
Aminoglycoside | Smlt0191 | Putative aminoglycoside phosphotransferase |
Aminoglycoside | Smlt1669 | Putative aminoglycoside 2' N-acetyltransferase |
Aminoglycoside | Smlt2120 | Known aminoglycoside 3' phosphotransferase |
Streptomycin | Smlt2336 | Putative streptomycin 3" phosphotransferase/kinase |
Aminoglycoside | Smlt3615 | Known aminoglycoside 6'N acetyltransferase |
Spectinomycin | Smlt2125/spcN | Putative spectinomycin phosphotransferase |
Chloramphenicol | Smlt0620/cat | Putative chloramphenicol acetyltransferase |
Fluoroquinolone | Smlt1071/qnrB | Putative quinolone resistance protein |
Macrolides | Smlt0032 | Putative MFS-type tripartite efflux transporter |
Macrolides | Smlt1537-9 | Putative ABC-type tripartite efflux transporter |
Macrolides | Smlt2642-3 | Putative ABC efflux transporter and MFP |
Multidrug | Smlt1528-30/emrA,emrB | Putative MFS-type tripartite efflux transporter |
Multidrug | Smlt1830-31;33/smeVWX | Putative RND-type tripartite efflux transporter |
Multidrug | Smlt2201-2/smeYZ | Putative RND-type efflux protein and MFP |
Multidrug | Smlt2796-8 | Multidrug/fusaric acid resistance protein |
Multidrug | Smlt3170-1/smeGH | Putative RND-type efflux protein and MFP |
Multidrug | Smlt3787-78/smeMN | Putative RND-type efflux protein and MFP |
Multidrug | Smlt3924-25/smeOP | Putative RND-type efflux protein and MFP |
Multidrug | Smlt4072-74/smeDEF | Known RND-type tripartite efflux protein |
Multidrug | Smlt4279-81/smeJKL | Putative RND-type tripartite efflux proteins and MFP |
Multidrug | Smlt4474-76/smeABC | Known RND-type tripartite efflux protein |
Beta-lactams | bla L1 | Known Beta-lactamase - L1 |
Beta-lactams | bla L2 | Known Beta-lactamase - L2 |
Kasuagamycin | ksgA | Putative kasuagamycin resistance protein |
Organic solvents | ostA | Organic solvent tolerance protein |
Peroxide | ohrA | Organic hydroperoxide |
Mercury | merRTPA | Mercury resistance |
Copper | copLABMGCDF Smlt2445/Smlt2443 copL2A2B2 copCD | Copper resistance |
Arsenic | arsRCHR2C2B Smlt2420 | Arsenic resistance |