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Table 3 Highly enriched leishmania secreted proteins

From: Proteomic analysis of the secretome of Leishmania donovani

GeneDB accession number Protein identificationa Mean Cm/CA ratiob Functionc Predicted locationc
LmjF14.1360 Myo-inositol-1-phosphate synthase 3.93 Inositol biosynthesis [50] Cytosol
LmjF23.0200 Endoribonuclease L-PSP (pb5), putative 3.91 Nuclease, mRNA cleavage Cytosol
LmjF15.1203 60S acidic ribosomal protein P2 3.73 Translation [102] Ribosomed
LmjF35.2420 Phosphoinositide-binding protein, putative 3.51 Phosphoinositol binding, signal transduction Cytosold
LmjF16.0140 Eukaryotic translation initiation factor 1A, putative 3.26 Translation Cytosol, exosomes [24,38,39]
LmjF32.2180 Hypothetical protein, conserved 3.08 Translation initiation Nucleus
LmjF11.0630 Aminopeptidase, putative, metallo-peptidase, Clan MF, Family M17 3.05 Proteolysis Cytosol
LmjF35.3340 6-Phosphogluconate dehydrogenase, decarboxylating, putative 3.01 Glucose cataboloism Cytosol
LmjF04.0310 Beta-fructofuranosidase, putative 2.93 Carbohydrate metabolism Cytosold
LmjF36.3840 Glycyl tRNA synthetase, putative 2.87 Translation Cytosol
  1. aThe Mascot algorithm {2008 609/id} was used to identify the protein names and the GeneDB accession numberes [29]. bMean of normalized, log normal (Ln) transformed conditioned medium (Cm)/cell associated (CA) peptide ratios for at least three of four experiments. cPutative functions and locations are derived from the GeneDB database {2007 238/id}unless otherwise noted. *Protein sequence contains an amino-terminal secretion signal peptide according to SignalP.