Figure 1From: FitSNPs: highly differentially expressed genes are more likely to have variants associated with diseaseUse of differentially and constantly expressed genes to rediscover disease genes. The DER was calculated as the count of GEO datasets in which a gene was differentially expressed divided by the count of GEO datasets in which it was measured. For any cutoff x, differentially expressed genes were defined as genes with DER > x, whereas constantly expressed genes were defined as genes with DER <x. The precision/recall graphs show that the likelihood of harboring disease mutations for a gene increases when its DER value increases. For the control, we shuffled disease labels 10,000 times among all genes and obtained a predicted precision of 16%. DER, differential expression ratio; GEO, Gene Expression Omnibus.Back to article page