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Figure 4 | Genome Biology

Figure 4

From: Functional architecture of Escherichia coli: new insights provided by a natural decomposition approach

Figure 4

FFs bridge modules and shape the backbone of the hierarchy governing the TRN. (a) Remaining TFs after cumulative removal of hierarchical nodes. The removal of all hierarchical nodes decreased to 3.5% the total FFs. (b) Correlation between FF number and maximum connectivity for each attacked network. The FF number is proportional to the number of links of the most-connected hierarchical node, thus suggesting that FFs are the backbone of the hierarchy in the TRN.

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