Figure 2From: Protein interactions in human genetic diseasesROC curves calculated on a set of alanine scanning experiments. The red line represents the performance of our algorithm when changing only the conservation threshold, applying no percentage identity cutoff. The green line shows the performance using only percentage identity as a threshold. The blue line reflects performance using conservation as threshold, but applying a 30% sequence identity filter. Confidence intervals where calculated using the Statistics::ROC Perl module [59].Back to article page