Table 4 Specific transcriptomic signatures identified in the leukocyte populations studied
| Â | Expression ratio (log2) of specific genes* | |||
|---|---|---|---|---|
Cell type | 3-4 | 2-3 | 1-2 | 0,4-1 |
Myeloid cells | - | Steap4; Clec4d; Clec4e; Fpr1 | Nfe2; Mpp1; Snca; Ccr1; Slc40a1; S100a9; Cd14; Tlr4 ; F5; Fcgr3; Fpr-rs2; Tlr2 ; Abhd5; Gca; Atp6v1b2; Ier3; Sod2; Pilra; Slc11a1 | Sepx1; Ninj1; Hp; Sdcbp; Bst1; Ifit1; S100a8; Adipor1; Bach1; Marcks; Pira2; Wdfy3; Ifrd1; Fcho2; Csf3r ; C5ar1; Cd93; Snap23; Cebpb; Clec7a; Yipf4; Hmgcr; Slc31a2; Fbxl5 |
Pan-DC | Â | Flt3 | Sh3tc1 | Trit1; Bri3bp; Prkra; Etv6; Tmed3; Bahcc1; Scarb1 |
cDC | - | - | Arhgap22; Btbd4; Slamf8; 9130211I03Rik; Nav1 | C2ta ; Avpi1; Spint1; Cs |
pDC | Â | Epha2 ; Pacsin1; Zfp521; Sh3bgr | Tex2; Runx2; Atp13a2; Maged1; Tm7sf2; Tcf4; Gpm6b; Cybasc3 | Nucb2; Alg2; Pcyox1; LOC637870; Scarb2; Dnajc7; Trp53i13; Plac8 ; Pls3; Tlr7 ; Ptprs; Bcl11a |
B cells | Ebf1 ; Cd19 ; Klhl14 | Bank1 ; Pax5 | Blr1 ; Ralgps2; Cd79b ; Pou2af1 ; Fcer2a; Cr2; Cd79a ; Fcrla | Ms4a1; Blk ; Cd72 ; Syvn1; BC065085; Fcrl1; Phtf2; Tmed8; Grap; Pip5k3; Pou2f2 |
NK cells | - | Ncr1 | Tbx21 ; Osbpl5 | Rgs3; 1700025G04Rik; Plekhf1; Fasl ; Zfpm1; Edg8 ; Cd160 ; Klrd1 ; Il2rb ; Il18rap ; Ctsw; Ifng ; Prf1 ; Sh2d2a; Llgl2; Gpr178; Prkx; Gab3; Nkg7 ; Cst7; Sntb2; Runx3; Myo6; F2r; Vps37b; Dnajc1; Gfi1 |
Pan-T cells | - | Camk4 ; E430004N04Rik; Trat1 | Cxcr6 ; Tnfrsf25; Ccdc64; Plcg1 | Cd3e ; Cd5 ; Lrig1; Cd3g ; Ubash3a; Cd6 ; Lat ; Bcl11b; Tcf7 ; Icos |
CD8 T cells | - | - | - | Gzmk |
CD4 T cells | - | Ctla4 | - | Icos ; Tnfrsf25; Cd5 ; Cd28 ; Trat1 |
Lymphocytes | - | - | Ablim1; Lax1; D230007K08Rik; Rasgrp1; Bcl2 | Spnb2; Cdc25b; Ets1 ; Sh2d2a; Ppp3cc; Cnot6l |
Myeloid, B, DC | - | H2-DMb2 ; H2-DMb1 | C2ta ; March1 ; Aldh2; Bcl11a; Btk | Ctsh ; H2-Eb1 ; Cd74 ; Ctsz ; Clic4; Kynu ; 5031439G07Rik; Nfkbie; Unc93b1 |
Non-DC | Gimap4 | - | Vps37b | Lck ; Pde3b |