Table 2 Overview of genes that are differentially expressed in response to cholesterol
| Â | LC | HC | ||||
|---|---|---|---|---|---|---|
GO category | Up | Down | Total | Up | Down | Total |
Lipid and lipoprotein metabolism (includes cholesterol and steroid metabolism) | 8 | 50 | 58 | 37 | 114 | 151 |
Protein metabolism (includes protein folding and breakdown) | 34 | 14 | 48 | 143 | 98 | 241 |
Other metabolism (includes carbohydrate metabolism) | 32 | 19 | 51 | 122 | 130 | 252 |
Generation of precursor metabolites and energy | 10 | 15 | 25 | 24 | 47 | 71 |
Transport | 31 | 15 | 46 | 125 | 77 | 202 |
Immune and stress response/inflammation | 19 | 7 | 26 | 99 | 49 | 148 |
Cell proliferation/apoptosis | 9 | 3 | 12 | 37 | 18 | 55 |
Cell adhesion/cytoskeleton | 10 | 1 | 11 | 76 | 8 | 84 |