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Table 1 Across experiment comparison of protein subsets associated with systematic error

From: Coverage and error models of protein-protein interaction data by directed graph analysis

 

Not in Krogan et al. [11]

In Krogan et al. [11]

Not in Gavin et al. [10]

624

63

In Gavin et al. [10]

31

12

 

P = 6.5 × 10-4

Odds ratio = 3.82

  1. This table compares the proteins affected by a reciprocity artifact from the datasets of Gavin and coworkers [10] and Krogan and colleagues [11]. Binomial tests were applied to identify the affected protein sets within each experiment, and their overlap was assessed in the 2 × 2 contingency table. In this table, the binomial tests were applied to the two experimental datasets independently, and only those proteins in which the in-degree is much larger than the out-degree are considered. Shown P value and odds ratio were calculated from the 2 × 2 table using the hypergeometric distribution.