Table 2 Functional annotations enriched among genes upregulated* in BMP2+ cells compared to control cells in seven-day-old EBs and undifferentiated BMP2 ES cells
Category | Term | Count | p value |
|---|---|---|---|
GOTERM_MF_5 | Zinc ion binding | 46 | 5.6E-5 |
GOTERM_CC_5 | Nucleus | 95 | 3.3E-4 |
GOTERM_BP_5 | Cellular protein metabolism | 66 | 3.3E-4 |
GOTERM_BP_5 | Protein catabolism | 10 | 4.9E-3 |
GOTERM_BP_5 | Apoptosis | 17 | 5.9E-3 |
GOTERM_BP_5 | Biopolymer modification | 38 | 6.0E-3 |
GOTERM_BP_5 | Biopolymer catabolism | 10 | 6.9E-3 |
GOTERM_BP_5 | Positive regulation of programmed cell death | 8 | 9.1E-3 |
GOTERM_MF_5 | ATP binding | 30 | 1.4E-2 |
GOTERM_BP_5 | Response to unfolded protein | 5 | 1.5E-2 |
GOTERM_BP_5 | Transcription | 47 | 1.5E-2 |
GOTERM_BP_5 | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism | 45 | 2.7E-2 |
GOTERM_BP_5 | Regulation of programmed cell death | 11 | 3.8E-2 |
GOTERM_BP_5 | Regulation of progression through cell cycle | 11 | 5.1E-2 |
GOTERM_BP_5 | Protein kinase cascade | 8 | 5.3E-2 |
GOTERM_BP_5 | Regulation of protein kinase activity | 5 | 5.6E-2 |
GOTERM_BP_5 | Small GTPase mediated signal transduction | 9 | 5.6E-2 |
GOTERM_BP_5 | Post replication repair | 2 | 6.2E-2 |
GOTERM_MF_5 | Ubiquitin-protein ligase activity | 8 | 6.2E-2 |
GOTERM_BP_5 | Regulation of apoptosis | 10 | 7.4E-2 |
GOTERM_BP_5 | Protein transport | 16 | 7.5E-2 |
GOTERM_MF_5 | Protein kinase activity | 15 | 8.3E-2 |
KEGG_REACTION | Phytoceramide+h2o<=>fattyacid+phytosphingosine | 3 | 8.7E-2 |
GOTERM_CC_5 | Lytic vacuole | 6 | 8.8E-2 |
KEGG_PATHWAY | MAPK signaling pathway | 9 | 9.5E-2 |