Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics

Table 3 Unique enzymes of A. niger in comparison to selected filamentous fungi

EC no.	CBS 513.88	ATCC 9029	KO no.	KO definition	Closest homolog in A. niger CBS 513.88	E-value	Identity (%)	Closest homolog in other Aspergilli	E-value	Identity (%)	Functional category
1.3.1.11	An12g02790	*		Coumarate reductase	An12g02420	5E-43	36	Afu5g09450	3E-57	39	Phenylalanine degradation
2.3.1.18	An13g03730	Anig05994		Galactoside O-acetyltransferase	An01g14790	9E-22	44	MG02103	1E-27	50	Carbon metabolism
3.6.3.41	An05g02470	Anig06282 Anig10968	K02021	ABC transport system ATP-binding protein	An08g04860	0	33	FG02316	0	30	Transport
5.4.99.-	An08g09210	Anig02930	K01865	S-adenosylmethionine tRNA ribosyltransferase							tRNA modification
4.2.1.94	An08g09920	Anig07347		Scytalone dehydratase				FG06477	7E-17	32	Biosynthesis of melanin
4.2.3.19	An11g06270	Anig08665	K04121	Ent-kaurene synthase	An18g02710	1.5E-67	31	AN1594	3E-78	31	Diterpenoid biosynthesis
2.5.1.39	An10g00130	Anig10859	K03179	4-Hydroxybenzoate octaprenyltransferase	An16g02750	7E-56	41	FG10613	7E-20	31	Ubiquinone biosynthesis
1.13.11.3	An02g11530	Anig09276	K00449	Protocatechuate 3,4-dioxygenase, beta subunit	An01g12310	2.7E-71	46	AN9363	3E-73	46	Benzoate and 2,4-dichlorobenzoate degradation
4.1.1.55	An15g07340	Anig08580	K04102	4,5-Dihydroxyphthalate decarboxylase							2,4-Dichlorobenzoate degradation

*: a genomic sequence nearly identical to An12g02790 was found in A. ngier ATCC 9029 but not annotated as a gene by the automatic genome annotation procedure described in Materials and methods.

ISSN: 1474-760X