A proteome-wide protein interaction map for Campylobacter jejuni

Table 2 Comparison of C. jejuni, H. pylori, and E. coli protein interaction sets to an E. coli reference set containing 599 low-throughput literature-cited interactions*

	Reference set interologs^†	Overlap with reference set interologs	Overlap (%) with total interactions detected for each study	Fraction of proteins in each study with orthologs in the reference set
C. jejuni	147	28 (19%)	0.24	7.9%
C. jejuni (HC)	147	27 (18%)	0.95	8.5%
H. pylori ^‡	84	10 (12%)	0.70	7.9%
E. coli ^§	599	81 (14%)	1.32	11.2%
E. coli ^¶	599	49 (8%)	0.44	11.2%

*The reference set was derived from DIP [28]. ^†Interolog lists were generated separately for each organism based on BLASTP reciprocal best match determination of orthologs. ^‡H. pylori interactions were detected by Rain et al. [11]. ^§E. coli interactions were predicted from Butland et al. [1]. ^¶E. coli interactions were predicted from Arrifuzzaman et al. [6]. HC, high confidence set.

ISSN: 1474-760X