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Table 1 Suspicious regions in the human chromosome 1 alignment

From: Measuring the accuracy of genome-size multiple alignments

Species

Aligned residues

Residues in suspicious regions

Suspicious regions

Residues with high phastCons score in suspicious regions

Chimp

211,636,048

(86%)

7,722

(0.004%)

103

174

(2.3%)

Rhesus

198,482,753

(80%)

32,789

(0.02%)

358

214

(0.7%)

Rabbit

87,544,213

(35%)

2,053,030

(2.3%)

24,210

24,037

(1.2%)

Mouse

92,668,918

(37%)

3,033,524

(3.3%)

36,594

25,175

(0.8%)

Rat

87,532,024

(35%)

3,141,584

(3.6%)

37,231

34,373

(1.1%)

Dog

132,538,114

(54%)

1,661,141

(1.3%)

19,277

8,383

(0.5%)

Cow

124,582,989

(50%)

1,524,553

(1.2%)

18,020

6,563

(0.4%)

Armadillo

81,991,879

(33%)

1,451,731

(1.8%)

17,306

25,172

(1.7%)

Elephant

88,888,989

(36%)

2,047,450

(2.3%)

23,089

30,143

(1.5%)

Tenrec

67,619,223

(27%)

2,495,171

(3.7%)

26,697

26,611

(1.1%)

Opossum

31,534,309

(13%)

4,657,853

(14.8%)

41,302

120,445

(2.6%)

Chicken

9,106,790

(4%)

2,363,996

(26.0%)

18,397

235,152

(9.9%)

Frog

5,916,044

(2%)

1,432,427

(24.2%)

10,947

219,613

(15.3%)

Tetraodon

5,167,534

(2%)

1,765,895

(34.2%)

9,508

240,568

(13.6%)

Fugu

4,630,234

(2%)

1,167,357

(25.2%)

8,437

169,851

(14.6%)

Zebrafish

5,855,213

(2%)

1,669,490

(28.5%)

10,963

324,159

(19.4%)

All species

219,711,964

(89%)

21,334,060

(9.7%)

185,452

1,127,826

(5.3%)

  1. Aligned portions of the 247 Mbp of human chromosome 1 with respect to each of the other 16 vertebrates. Column 2 shows the total number of residues of human chromosome 1 that are aligned to the other species, together with its percentage of 247 Mbp, the size of human chromosome 1. Column 3 shows the total number of residues that are in suspicious regions, together with its percentage of the corresponding number in column 2. The number of suspicious regions is shown in column 4. Column 5 shows the total number of residues that are in suspicious regions and have a phastCons score greater than 0.5, together with its percentage of the corresponding number in column 3.