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Figure 4 | Genome Biology

Figure 4

From: Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes

Figure 4

Alignment of 15q11-q13 clones in duplicons adjacent to segment V. (a) The three representative clones containing segment V are aligned, with single nucleotide variants in a 3,356 base pair (bp) region of segment V in all sequenced RP11 clones shown below. The asterisk above segment V indicates its orientation, as in Figure 1. The box shows the number of mismatches between each pair of haplotigs. (b) Corrected alignment of clones to show true relationship between ends of contigs NT_010280 and NT_078096. The hash above segment V of RP11-536P16 is to indicate that its orientation has been inverted compared with that in the database. (c) Alignment of clones around the segment V end of contig NT_078094, with single nucleotide variants in a 9.5 kilobase (kb) region around the small segment P shown below.

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Genome Biology

ISSN: 1474-760X

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