Figure 3
From: Functional coordination of alternative splicing in the mammalian central nervous system
Detection of new motifs in exons and introns that correlate with CNS regulated AS events. Motifs correlating with central nervous system (CNS) associated alternative splicing (AS) levels were detected in exon sequences (C1, A, C2) and intron sequences (I1, I2) using the SeedSearcher algorithm [41]. Ab initio searches for motifs were performed in the individual exon and intron sequences, and in concatenations of intron/exon sequences. Motifs enriched in these locations, as indicated by lines with arrowheads, are correlated with either increased inclusion (yellow boxes), increased exclusion (blue boxes), or a change in inclusion (black boxes), respectively.