Table 7 Comparison of gene expression in the T4 and T1 cell fractions by real-time PCR
From: Large-scale identification of human genes implicated in epidermal barrier function
No. of ORESTES | Gene symbol | Full name | No. of UniGene ESTs | T4/T1 expression ratio |
|---|---|---|---|---|
56 | FLG2 | Filaggrin 2 (ifapsoriasin) | 10 | 800 |
9 | GSDM1 | Gasdermin 1 | 16 | 800 |
13 | ASAH3 | N-acylsphingosine amidohydrolase 3 | 4 | 300 |
2 | IL1F7 | Interleukin 1 family, member 7 | 17 | 200 |
13 | ELMOD1 | ELMO/CED-12 domain containing 1 | 62 | 160 |
0 | LIPL4 (LIPN) | Lipase-like, ab-hydrolase domain containing 4 | 9 | 150 |
1 | LIPL3 (LIPM) | Lipase-like, ab-hydrolase domain containing 3 | 20 | 130 |
3 | C20orf95 | Chromosome 20 open reading frame 95 | 28 | 120 |
1 | WFDC12 | WAP four-disulfide core domain 12 (WAP2) | 3 | 110 |
1 | LIPL2 (LIPK) | Lipase-like, ab-hydrolase domain containing 2 | 4 | 100 |
12 | SMPD3 | Sphingomyelin phosphodiesterase 3 | 98 | 70 |
10 | LOC440449 | Similar to WDNM1 homolog (LOC645638) | - | 50 |
99 | SERPINA12 | Serpin peptidase inhibitor, clade A, member 12 | 11 | 50 |
1 | P11 | 26 serine protease | 64 | 35 |
5 | PSORS1C2 | Psoriasis susceptibility 1 candidate 2 | 8 | 30 |
1 | C3orf52 | Chromosome 3 open reading frame 52 | 90 | 30 |
2 | CLDN23 | Claudin 23 | 76 | 25 |
1 | PNPLA1 | Patatin-like phospholipase domain containing 1 | 15 | 20 |
10 | THEM5 | Thioesterase superfamily member 5 | 26 | 20 |
3 | ABHD9 | Abhydrolase domain containing 9 | 51 | 20 |
2 | TMEM16H | Transmembrane protein 16H | 78 | 16 |
6 | SERPINB12 | Serpin peptidase inhibitor, clade B, member 12 | 6 | 15 |
1 | PLEKHN1 | Pleckstrin homology domain containing, family N member 1 | 12 | 12 |
1 | FAM83F | Family with sequence similarity 83, member F | 49 | 12 |
3 | AADACL2 | Arylacetamide deacetylase-like 2 | 20 | 12 |
10 | LOC342897 | Similar to F-box only protein 2 | 21 | 10 |
9 | LASS3 | LAG1 longevity assurance homolog 3 | 53 | 10 |
20 | CASZ1 | Castor homolog 1, zinc finger | 61 | 10 |
8 | FAM46B | Family with sequence similarity 46, member B | 62 | 10 |
14 | SERPINB7 | Serpin peptidase inhibitor, clade B, member 7 | 64 | 10 |
1 | CARD14 | Caspase recruitment domain family, member 14 | 86 | 8 |
1 | GGT6 | Gamma-glutamyltransferase 6 homolog | 27 | 6 |
1 | CXorf33 | Chromosome X open reading frame 33 | 52 | 6 |
10 | WFDC5 | WAP four-disulfide core domain 5 (WAP1) | 11 | 1 |
5 | KIAA0514 | Kiaa0514 | 16 | 1 |
5 | AMIGO3 | Adhesion molecule with Ig-like domain 3 | 18 | 1 |
3 | PLA2G4E | Phospholipase A2, group IVE | 28 | 1 |
1 | HSPC105 | NAD(P) dependent steroid dehydrogenase-like | 45 | 1 |
3 | PLA2G4F | Phospholipase A2, group IVF | 56 | 1 |
127 | DUOX2 | Dual oxidase 2 | 64 | 1 |
1 | APXL2 | Apical protein 2 | 74 | 1 |
3 | RAB38 | RAB38, member RAS oncogene family | 79 | 1 |
1 | AFMID | Arylformamidase | 87 | 1 |
2 | ANKRD5 | Ankyrin repeat domain 5 | 86 | 0.46 |
3 | MCMDC1 | Minichromosome maintenance deficient domain containing 1 | 43 | 0.4 |
1 | C14orf21 | Chromosome 14 open reading frame 21 | 54 | 0.38 |
3 | LEAP-2 | Liver-expressed antimicrobial peptide 2 | 53 | 0.36 |
1 | LRP5L | Low density lipoprotein receptor-related protein 5-like | 41 | 0.35 |
4 | FNDC6 | Fibronectin type III domain containing 6 | 79 | 0.3 |
2 | KIAA1287 | Kiaa1287 | 91 | 0.28 |