Table 2 Functions specific to human-pathogenic strains (holarctica and tularensis)

Sequences specific to human pathogenic strains

FTT0016

FTL_1849

192

30.0

-

Hypothetical protein FTT0016

Hypothetical

FTT0300

FTL_0211

284

27.4

-

Hypothetical protein FTT0300

Hypothetical

FTT0301

FTL_0212

289

29.5

-

Hypothetical protein FTT0301

Hypothetical

FTT0376c

FTL_1314

352

28.1

-

Hypothetical membrane protein

Hypothetical

FTT0395

FTL_0415

237

29.3

-

Hypothetical protein FTT0395

Hypothetical

FTT0430

FTL_0461

144

34.6

speH

S-adenosylmethionine decarboxylase

Other metabolism

FTT0431

FTL_0499

289

33.1

speE

Spermidine synthase

Other metabolism

FTT0434

FTL_0500

328

33.7

-

Hypothetical protein FTT0434

Other metabolism

FTT0524

FTL_0977

128

28.4

-

Hypothetical protein FTT0524

Hypothetical

FTT0572

FTL_1339

484

31.5

-

Proton-dependent oligopeptide transport (POT) family protein

Transport

FTT0601

FTL_0780

39

31.6

-

Hypothetical protein FTT0601

Hypothetical

FTT0602c

FTL_0867

492

31.1

-

Hypothetical protein FTT0602c

Hypothetical

FTT0603

FTL_0870

59

30.3

-

Hypothetical protein FTT0603

Hypothetical

FTT0604

FTL_0872

144

31.2

-

Hypothetical protein FTT0604

Hypothetical

FTT0727

FTL_1512

226

29.4

-

Hypothetical protein FTT0727

Hypothetical

FTT0728

FTL_1513

310

33.2

ybhF

ABC transporter, ATP-binding protein

Transport

FTT0729

FTL_1515

372

30.4

ybhR

ABC transporter, membrane protein

Transport

FTT0794

FTL_1427

428

30.3

-

Hypothetical protein FTT0794

Hypothetical

FTT0795

FTL_1426

227

25.5

-

Hypothetical protein FTT0795

Hypothetical

FTT0796

FTL_1425

253

23.2

-

Hypothetical protein FTT0796

Hypothetical

FTT0958c

FTL_1245

235

33.2

-

Short chain dehydrogenase

Cell wall/LPS/capsule

FTT1079c

FTL_1123

86

37.3

-

Hypothetical protein FTT1079c

Hypothetical

FTT1172c

FTL_0777

143

29.4

csp

Cold shock protein (DNA binding)

Signal transduction and regulation

FTT1174c

FTL_0776

69

24.5

-

Hypothetical protein FTT1174c

Hypothetical

FTT1175c

FTL_0759

212

25.5

-

Hypothetical membrane protein

Hypothetical

FTT1188

FTL_0668

211

28.8

-

Hypothetical membrane protein

Hypothetical

FTT1307c

FTL_0211

178

34.5

-

Hypothetical protein FTT1307c

Hypothetical

FTT1395c

FTL_0605

476

30.6

-

ATP-dependent DNA helicase

Signal transduction and regulation

FTT1451c

FTL_0604

294

38.4

wbtL

Glucose-1-phosphate thymidylyltransferase

Cell wall/LPS/capsule

FTT1452c

FTL_0603

286

29.4

wbtK

Glycosyltransferase

Cell wall/LPS/capsule

FTT1453c

FTL_0602

495

30.1

wzx

O-antigen flippase

Cell wall/LPS/capsule

FTT1454c

FTL_0598

241

28.9

wbtJ

Hypothetical protein FTT1454c

Cell wall/LPS/capsule

FTT1458c

FTL_0594

409

22.2

wzy

Membrane protein/O-antigen protein

Cell wall/LPS/capsule

FTT1462c

FTL_0527

263

29.7

wbtC

UDP-glucose 4-epimerase

Cell wall/LPS/capsule

FTT1581c

FTL_0511

94

28.5

-

Endonuclease

Mobile and extrachromosomal element functions

FTT1594

FTL_1634

330

30.8

-

Transcriptional regulator, LysR family

Signal transduction and regulation

FTT1595

FTL_1633

51

26.9

-

Hypothetical protein FTT1595

Hypothetical

FTT1596

FTL_1632

132

32.1

-

Hypothetical protein FTT1596

Hypothetical

FTT1597

FTL_1631

485

30.3

-

Hypothetical protein FTT1597

Hypothetical

FTT1614c

FTL_0502

227

31.6

-

Hypothetical protein FTT1614c

Hypothetical

FTT1659

FTL_0034

341

26.0

-

Hypothetical protein FTT1659

Hypothetical

Genes inactivated in novicida but functional in human pathogenic strains

FTT0707

FTL_1529

264

26.9

-

Nicotinamide mononucleotide transport (NMT) family protein

Transport

FTT1090

FTL_1113

225

27.6

-

Hypothetical protein

Hypothetical

FTT1076

FTL_1125

424

31.1

hipA

Transcription regulator

Signal transduction and regulation

FTT0666c

FTL_0940

193

29.5

-

Methylpurine-DNA glycosylase family protein

DNA metabolism

FTT1450c

FTL_0606

348

33.6

wbtM

dTDP-D-glucose 4,6-dehydratase

Cell wall/LPS/capsule