Gene name | Gene description | RefSeq | Orthloga | Number of TFBSs predictedb | Functional annotationc | ||||
---|---|---|---|---|---|---|---|---|---|
p53 | NF-κB | AP-1 | STAT3 | EGR1 | |||||
Cluster A | |||||||||
ABCC5 | ATP-binding cassette, subfamily C (CFTR/MRP), member 5 | NM_005688 | hmra | 1 (hmr) | Transport | ||||
ARID1A | AT rich interactive domain 1a (SWI-like) | NM_006015 | hmr | 1 (hmr) | 5 (hmr) | Regulation of metabolism | |||
ARTS-1 | Type 1 TNF receptor shedding aminopeptidase regulator | NM_016442 | hmr | 1 | 1 | 1 | 1 | Catabolism | |
ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | NM_001679 | hmr | 3 | 7 | Transport | |||
BLK | B lymphoid tyrosine kinase | NM_001715 | hmr | 1 | Signal transduction | ||||
CDC42EP4 | cdc42 effector protein 4; binder of Rho GTPases 4 | NM_012121 | h | 1 | 2 | 2 | Regulation of cell shape | ||
CDH18 | Cadherin 18, type 2 | NM_004934 | h | Cell adhesion | |||||
CDKN2C | Cyclin-dependent kinase inhibitor 2C (p18) | NM_078626 | hmr | 3 | 1 | Cell proliferation; cell cycle | |||
CKB | Creatine kinase, brain | NM_001823 | hmr | 3 | 8 | Creatine kinase activity | |||
CPS1 | Carbamoyl-phosphate synthetase 1, mitochondrial | NM_001875 | hmr | 2 (hmr) | 1 | 1 (hmr) | Amino acid metabolism | ||
FZD1 | Frizzled homolog 1 (Drosophila) | NM_003505 | h | 1 | 4 | Signal transduction | |||
HARSL | Histidyl-tRNA synthetase-like | NM_012208 | hm | 2 | 1 | 1 | Amino acid metabolism | ||
HBE1 | Hemoglobin, epsilon 1 | NM_005330 | hr | 1 | 1 | Transport | |||
HIST1H2AC | H2A histone family, member L | NM_003512 | h | 1 | Chromosome organization and biogenesis | ||||
HIST1H2AM | H2A histone family, member N | NM_003514 | h | 3 | Chromosome organization and biogenesis | ||||
HIST1H2BC | H2B histone family, member L | NM_003526 | h | 1 | Chromosome organization and biogenesis | ||||
HIST1H2BD | H2B histone family, member B | NM_138720 | hr | 1 | 1 | Chromosome organization and biogenesis | |||
HIST1H2BJ | H2B histone family, member R | NM_021058 | h | 1 | 1 | Chromosome organization and biogenesis | |||
HIST1H2BL | H2B histone family, member C | NM_003519 | h | 1 | Chromosome organization and biogenesis | ||||
HIST1H2BN | H2B histone family, member D | NM_003520 | h | 2 | 2 | Chromosome organization and biogenesis | |||
HIST2H2BE | H2B histone family, member Q | NM_003528 | h | 3 | 1 | 1 | 1 | Chromosome organization and biogenesis | |
IGFBP2 | Insulin-like growth factor binding protein 2 (36 kDa) | NM_000597 | hmr | 1 (hr) | 4 (hmr) | Regulation of cell growth | |||
LGALS3BP | Lectin, galactoside-binding, soluble, 3 binding protein | NM_005567 | hmr | 1 | 2 (hmr) | Cell adhesion | |||
MATN2 | Matrilin 2 | NM_002380 | h | 1 | Extracellular matrix assembly | ||||
MYST3 | MYST histone acetyltransferase (monocytic leukemia) 3 | NM_006766 | hmr | 5 (hmr) | 6 (hmr) | DNA packaging | |||
OLFM1 | Olfactomedin 1 | NM_014279 | hmr | 1 | 1 | 2 | 4 (hmr) | Morphogenesis | |
PRODH | Proline oxidase homolog | NM_016335 | h | Amino acid metabolism | |||||
SLC9A3R1 | Solute carrier family 9, isoform 3 regulatory factor 1 | NM_004252 | hmr | 1 | 3 (hr) | Signal transduction | |||
TDRD7 | Tudor domain containing 7 | NM_014290 | hmr | 1 | 1 (hmr) | 5 (hmr) | Protein amino-terminus binding | ||
TGM1 | Transglutaminase 1 | NM_000359 | hmr | 2 | 1 | 1 | Morphogenesis; cell proliferation | ||
THAP11 | THAP domain containing 11 | NM_020457 | h | 3 | DNA binding, ion binding | ||||
UBADC1 | Ubiquitin associated domain containing 1 | NM_016172 | hmr | 2 (hmr) | 7 (hmr) | Protein ubiquitination | |||
XCL1 | Chemokine (C motif) ligand 2 | NM_002995 | h | 2 | Signal transduction | ||||
XPA | Xeroderma pigmentosum, complementation group A | NM_000380 | hmr | 2 | 1 | 2 (hmr) | DNA repair | ||
Cluster B | |||||||||
ABCG2 | ATP-binding cassette, subfamily G (WHITE), member 2 | NM_004827 | h | 3 | 1 | 2 | Transport | ||
ACSL5 | Fatty-acid-coenzyme a ligase, long-chain 5 | NM_016234 | hmr | 1 (hmr) | 1 | Fatty acid metabolism | |||
AIF1 | Allograft inflammatory factor 1 | NM_001623 | hmr | Inflammatory response; cell cycle | |||||
AKAP12 | A kinase (PRKA) anchor protein (gravin) 12 | NM_005100 | hmr | 1 | 2 | 2 | Signal transduction | ||
ARID3A | AT rich interactive domain 3A (BRIGHT-like) | NM_005224 | hmr | 2 (hmr) | 1 | 3 | Regulation of transcription | ||
BCAT1 | Branched chain aminotransferase 1, cytosolic | NM_005504 | h | 1 | 1 | 2 | Cell cycle; amino acid metabolism | ||
BIRC2 | Baculoviral IAP repeat-containing 2 | NM_001166 | h | 2 | 2 | 1 | 2 | Antiapoptosis; signal transduction | |
CA9 | Carbonic anhydrase IX | NM_001216 | hmr | 1 (hmr) | 1 (hmr) | One-carbon compound metabolism | |||
CAP2 | Adenylyl cyclase-associated protein 2 | NM_006366 | hm | 1 | Signal transduction | ||||
CROC4 | Transcriptional activator of the c-fos promoter | NM_006365 | h | 1 | Cell proliferation | ||||
DMAP1 | DNA methyltransferase 1-associated protein 1 | NM_019100 | hmr | 3 (hr) | 1 | Regulation of transcription | |||
DNAH11 | Dynein, axonemal, heavy polypeptide 11 | NM_003777 | h | 4 | Transport | ||||
FADS3 | Fatty acid desaturase 3 | NM_021727 | hmr | 3 | 5 (hr) | Fatty acid metabolism | |||
ICAM1 | Intercellular adhesion molecule 1 (CD54) | NM_000201 | hmr | 2 (hmr) | 1 | 1 (hmr) | 3 | Cell adhesion | |
IL6 | Interleukin 6 (interferon, beta 2) | NM_000600 | hmr | 1 (hm) | 1 (hmr) | 1 (hmr) | 1 | Signal transduction; inflammatory response | |
IL8 | Interleukin 8 | NM_000584 | h | 1 | 1 | 1 | Signal transduction; inflammatory response | ||
KCNN4 | Intermediate conductance Ca-activated K channel protein 1 | NM_002250 | hmr | 1 | 3 (hmr) | 1 (hmr) | Transport | ||
KRT18 | Keratin 18 | NM_199187 | h | 1 | 1 | Structural molecule activity | |||
KRT8 | Keratin 8 | NM_002273 | hr | 2 | 2 | 1 (hr) | 2 | Structural molecule activity | |
MLPH | Melanophilin | NM_024101 | h | 1 | 2 | Transport | |||
Pfs2 | DNA replication complex GINS protein PSF2 | NM_016095 | h | 1 | 5 | DNA metabolism | |||
PLK1 | Polo-like kinase (Drosophila) | NM_005030 | hmr | 1 | 1 | 1 (hm) | Metabolism; cell proliferation | ||
PORIMIN | Pro-oncosis receptor inducing membrane injury gene | NM_052932 | h | 1 | 5 | Oncosis-like cell death | |||
PPP1R12A | Protein phosphatase 1, regulatory (inhibitor) subunit 12A | NM_002480 | hmr | 1 | 5 (hmr) | Regulation of organismal physiological process | |||
PTPRJ | Protein tyrosine phosphatase, receptor type, J | NM_002843 | h | 1 | 8 | Signal transduction | |||
RAB17 | RAB17, member RaS oncogene family | NM_022449 | h | 1 | 2 | Signal transduction | |||
RAD54L | RAD54-like (S. cerevisiae) | NM_003579 | hmr | 1 | 7 | DNA repair; cell cycle | |||
RPN2 | Ribophorin II | NM_002951 | hmr | 1 | 1 | 1 | 1 | Protein metabolism | |
SHANK2 | Cortactin binding protein 1 | NM_012309 | hmr | 2 | 2 | 4 | Signal transduction | ||
SNCG | Synuclein, gamma (breast cancer-specific protein 1) | NM_003087 | hmr | 1 | Pathogenesis | ||||
SRPX2 | Sushi-repeat protein | NM_014467 | hmr | 2 (hmr) | Electron transport | ||||
STC1 | Stanniocalcin 1 | NM_003155 | hmr | 1 | 3 (hmr) | Signal transduction | |||
STK6 | Serine/threonine kinase 15 | NM_198433 | hmr | 1 | Cell cycle | ||||
TOMM34 | Translocase of outer mitochondrial membrane 34 | NM_006809 | hmr | 3 (hmr) | 2 (hmr) | Protein metabolism | |||
TXNRD1 | Thioredoxin reductase 1 | NM_003330 | hmr | 1 | 2 | 1 (hmr) | Signal transduction | ||
YAP1 | Yes-associated protein 1, 65 kD | NM_006106 | hmr | 1 | 11(hmr) | Signal transduction | |||
ZNF239 | Zinc finger protein 239 | NM_005674 | h | 1 | Regulation of transcription |