Skip to main content

Table 1 Exonic regulatory sequences predicted to be changed following editing in the five exonic sites

From: RNA-editing-mediated exon evolution

  Site e1* Site e2* Site e3* Site e4* Site e5*
SF2/ASF   CACACCT (3.2/3.6)    CTCAGGA (4.8/NA)
SC35    AATCACAG (NA/4) AATCACAG (NA/2.6)  
SRp40   GCACACC (2.6/NA)    CTACTCA (NA/5.1)
      ACTCAGG (4.2/NA)
SRp55   TGCACA (NA/3.1)    
Ast AGTGCA§     TCAGGA
Burge¶¥ TGGTGG     GGGAGG
  GGTAGT     TCAGGA
hnRNP F      GGGA
  1. The sequence of the exonic splicing regulatory sequence is shown. The edited 'A' nucleotide is in bold (unless otherwise indicated). The numbers in parentheses indicate the binding score before/after editing; NA indicates no available score. *Edited sites: E1, position 19 in the Alu-exon; E2, position 24; E3, position 32; E4, position 33; E5, position 46. Predicted by ESEfinder [31]. Predicted by Goren et al. [28]. §This unedited ESR overlaps with both E1 and E2 sites. Predicted by RESCU-ESE [30]. ¥Sites E1 and E5 created two different hexamers for the edited and unedited position, according to RESCU-ESE [30].