Gene-expression patterns reveal underlying biological processes in Kawasaki disease

Table 1 Characteristics of patients

	Cohort 1 (n = 20)*	Cohort 2 (n = 64)*	Cohort 3 (n = 33)*
Sex	14 male, 6 female	44 male, 20 female	19 male, 14 female
Age in years^†	3.5 (0.4-12.6)	2.1 (0.35-15.6)	1.7 (0.1-4.5)
Coronary artery status^‡	11 N, 7 D, 2 A	33 N, 22 D, 9 A	26 N, 3 D, 4 A
IVIG response^§	14 R, 4 NR	45 R, 8 NR	22 R, 11 NR
Illness day, acute sample^†	Day 6 (4-12)	Day 6 (2-14)	Day 5 (3-7)
Illness day, subacute sample^†	Day 20 (12-24)¶	NA	NA
Illness day, convalescent sample^†	Day 47 (32-64)¶	NA	NA

*Seven individuals were in both cohort 1 and cohort 2; three additional individuals were in both cohort 1 and cohort 3. ^†Data presented as median (range). ^‡Arterial diameter determined by echocardiogram. N, normal; D, dilated; A; aneurysm. ^§R, IVIG responder; NR, IVIG non-responder. Two patients in cohort 1 and 11 in cohort 2 were treated with IVIG after illness day 10 and excluded from analysis of IVIG response. ^¶Additional samples were obtained from three patients less than 48 h after treatment with IVIG on illness days 7, 8, and 13; one additional sample was obtained from a fourth patient at a 1-year follow-up. NA, not applicable.

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