Figure 1

Volcano plots of miR expression in wild-type retina versus brain and mouse platform. Plots represent comparative miR expression profiles of (a) c57 retina versus c57 brain and (b) c57 retina versus mouse platform using Exiqon miR microarrays. X-axis indicate difference in expression level on a log₂ scale, whereas the y-axis represents corresponding P values (Student's t-test) on a negative log scale; more lateral and higher points mean more extensive and statistically significant differences, respectively. Red lines indicate differences of ± 1, and significance level of P = 0.05. miR, microRNA.