Table 4 Comparison with previous approaches based on gene expression response to TF deletion

COGRIM (B+/C+)

7.24 × e^-03

3.71 × e^-04

1.23 × e^-07

2.57 × e^-11

COGRIM (B-/C+)

6.31 × e^-03

1.01 × e^-03

3.29 × e^-03

4.40 × e^-03

Model I (B+/C+)

0.018

4.00 × e^-04

7.31 × e^-04

4.80 × e^-09

Model I (B-/C+)

0.012

8.14 × e^-03

1.07 × e^-03

7.95 × e^-03

MA-Networker

0.021

1.81 × e^-04

2.34 × e^-06

2.17 × e^-10

GRAM

0.259

0.281

1.14 × e^-05

1.54 × e^-04

ReMoDiscovery

0.102

7.73 × e^-03

0.364

3.23 × e^-10

ChIP binding data alone (B+)

0.194

0.036

9.80 × e^-04

1.96 × e^-04