Prediction performance with various weights on two priors. To examine the effect of our prior information on prediction, we used a restricted COGRIM model that assigned fixed weights w (ranging from 0 to 1) to the ChIP binding data. The x-axis represents the assigned weights and the y-axis represents the number of predicted true C/EBP-β targets in 16 validated ones (black square spots). The sampling procedure automatically assigned an appropriate weight 0.92 (variance 0.006) to ChIP-chip binding data (red diamond spot). C-EBP, CCAAT/enhancer-binding protein; ChIP, chromatin immunoprecipitation.