Figure 5

Predicted regulatory elements in the regulatory regions of miRNA genes. The annotation in the regulatory regions of (a) miR-9 and (b) miR-132/212, are shown. Each panel shows the positions of regulatory elements on a background annotation of genes and sequence conservations extracted from the UCSC genome browser. Not one protein-coding gene is present in both regions. The bottom part of each panel shows the conservation of human sequence when compared with other mammalian species. Aligned human sequences are denoted with vertical lines at aligned positions for mouse, rat and dog, respectively. The track denoted by 'conservation' plots the overall conservation levels of the human sequence in each region. The regulatory elements demonstrate higher levels of conservation and stand out from the background sequences.