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Table 3 Differentially expressed transcription factors, neurogenesis, and apoptosis genes

From: Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

 

Transcription factor (GO:0003700)

Neurogenesis (GO:0007399)

Apoptosis (GO:0006915)

 

Gene name

Location

Gene name

Location

Gene name

Location

Neuroblast > neuroblastoma

MLL

11q

APOE

19q

APOE

19q

 

NR0B1

Xp

GREM1

15q

PLAGL1

6q

 

RORA

15q

TFAP2B

6p

SCARB1

12q

 

TFAP2B

6p

  

TDGF1

3p

Neuroblast < neuroblastoma

ASCL1*

12q

ALK

2p

BCL2

18q

 

ATF3

1q

APBB2

4p

BCLAF1

6q

 

CNOT7

8p

ASCL1

12q

BIRC5

17q

 

CUTL2

12q

CDK5R1

17q

CCL2

17q

 

ETV6

12p

FEZ1

11q

CD2

1p

 

FOXC1

6p

GPI

19q

CD74

5q

 

HCLS1

3q

INHBA

7p

CIAPIN1

16q

 

IRF8

16q

LARGE

22q

CYCS

7p

 

KLF10

8q

MBNL1

3q

HTRA2

2p

 

MLX

17q

NEFH

22q

IER3

6p

 

NFE2L1

17q

NTRK3

15q

IGFBP3

7p

 

NFIB

9p

OLFM1

9q

INHBA

7p

 

NME2

17q

PPT1

1p

ITGB2

21q

 

RUNX1

21q

SERPINF1

17p

ITGB3BP

1p

 

SIX3

2p

SIX3

2p

LGALS1

22q

 

STAT1

2q

SLIT1

10q

LY86

6p

 

STAT3

17q

SOX11

2p

OPA1

3q

 

TAF10

11p

STAT3

17q

PRKCA

17q

 

TAF7

5q

TRAPPC4

11q

RNF130

5q

 

TFDP1

13q

  

STAT1

2q

 

TRIM22

11p

  

SULF1

8q

 

TSC22D1

13q

  

TNFRSF21

6p

 

ZNF91

19p

  

TUBB

6p

  1. Shown are differentially expressed genes in neuroblastoma versus neuroblasts that belong to GO terms transcription factor, neurogenesis, and/or apoptosis, with an indication of the chromosomal localization. GO, Gene Ontology.