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Table 1 GO analysis: neuroblast versus cortex samples

From: Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

GO

P value

n

GO description

More highly expressed in neuroblast compared to cortex

GO:0007399

5.94E-09

20

Neurogenesis

GO:0019226

1.12E-06

13

Transmission of nerve impulse

GO:0007268

5.39E-06

12

Synaptic transmission

GO:0001505

9.29E-05

5

Regulation of neurotransmitter levels

GO:0007267

2.76E-04

16

Cell-cell signaling

GO:0050877

3.17E-04

16

Neurophysiological process

GO:0046879

3.47E-04

3

Hormone secretion

GO:0006584

3.47E-04

3

Catecholamine metabolism

GO:0018958

4.72E-04

3

Phenol metabolism

GO:0048513

6.67E-04

22

Organ development

GO:0006836

6.96E-04

4

Neurotransmitter transport

GO:0009887

7.32E-04

21

Organogenesis

GO:0007154

1.21E-03

46

Cell communication

GO:0045055

1.25E-03

3

Regulated secretory pathway

GO:0007269

1.25E-03

3

Neurotransmitter secretion

GO:0046903

1.52E-03

8

Secretion

GO:0030072

2.09E-03

2

Peptide hormone secretion

GO:0030073

2.09E-03

2

Insulin secretion

GO:0016079

2.09E-03

2

Synaptic vesicle exocytosis

GO:0042423

2.09E-03

2

Catecholamine biosynthesis

GO:0006887

2.24E-03

4

Exocytosis

GO:0009653

2.77E-03

23

Morphogenesis

GO:0007218

3.25E-03

4

Neuropeptide signaling pathway

GO:0007275

3.26E-03

29

Development

GO:0046883

5.70E-03

2

Regulation of hormone secretion

GO:0030182

7.26E-03

2

Neuron differentiation

GO:0048489

8.98E-03

2

Synaptic vesicle transport

More highly expressed in cortex compared to neuroblast

GO:0016126

4.18E-07

5

Sterol biosynthesis

GO:0006694

9.28E-07

6

Steroid biosynthesis

GO:0008202

4.32E-06

7

Steroid metabolism

GO:0016125

2.93E-05

5

Sterol metabolism

GO:0044255

6.74E-05

9

Cellular lipid metabolism

GO:0006629

8.75E-05

10

Lipid metabolism

GO:0008610

1.39E-04

6

Lipid biosynthesis

GO:0006695

2.97E-04

3

Cholesterol biosynthesis

GO:0006066

1.17E-03

6

Alcohol metabolism

GO:0008203

4.69E-03

3

Cholesterol metabolism

GO:0044242

4.97E-03

2

Cellular lipid catabolism

GO:0006118

7.90E-03

5

Electron transport

  1. Shown are over-represented GO classes (biological process) (with P < 0.01 and at least two genes) in the list of genes that are more highly expressed in neuroblast than in cortex samples, and vice versa. GO, Gene Ontology.