Gene1 | Gene2 | Wild-type |
rrf-3
|
---|
 |  | Pheno Gene1 | Pheno Gene2 | Pheno Gene1 | Pheno Gene2 |
---|
lin-31
| - | 5% | - | 35% | - |
sma-4
| - | 100% | - | 100% | - |
unc-22
| - | 100% | - | 100% | - |
lon-2
| - | 100% | - | 100% | - |
lin-31
|
sma-4
| 2% | 100% | 20% | 100% |
lin-31
|
unc-22
| 2% | 100% | 26% | 100% |
lin-31
|
lon-2
| 4% | 100% | 13% | 100% |
sma-4
|
unc-22
| 100% | 100% | 100% | 100% |
sma-4
|
lon-2
| 100% | 0% | 100% | 0% |
unc-22
|
lon-2
| 100% | 100% | 100% | 100% |
- Wild-type and RNA interference (RNAi)-hypersensitive rrf-3 worms, respectively, were fed on selected bacterial strains of the C. elegans RNAi feeding library [2] targeting the genes lin-31, sma-4, unc-22, and lon-2. Independent RNAi phenotypes (Pheno Gene1, Pheno Gene2) were assessed when each gene was targeted individually and also for all possible pair-wise combinations of genes. Percentages represent penetrance of phenotypes.