Genome-wide detection and analysis of homologous recombination among sequenced strains of Escherichia coli

Table 4 MulitFun categories exhibiting unusual levels of allelic substitution among the four major lineages

HR detected	Genes	Percent recombined	χ² score	Multi-Fun Level 2 categories
5	144	3.5	4.52	Ribosome and peptidoglycan structure
10	237	4.2	5.47	Cell division, cell protection, and adaptation to stress
14	279	5.0	4.35	Protein-related information
20	329	6.1	2.94	RNA-related information
386	4,035	9.6	Not reported	All other functions (including unknown)
48	357	13.5	9.24	Building block biosynthesis
16	109	13.8	3.21	DNA-related information
7	40	17.5	3.56	Group translocators (PTS)
9	46	19.6	6.24	Motility

Categories with few members such as ribosome and peptidoglycan structure are combined together, as are three types of cell processes. We computed a χ² goodness-of-fit statistic for each category, but do not report p values because dependencies exist between categories.

ISSN: 1474-760X