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Table 1 GO analysis of repeat variants

From: Tandem repeat copy-number variation in protein-coding regions of human genes

Term GO id Variants Non-variants Statistical tests
   Linked Not linked Linked Not linked     
(a) Primary hypothesis          
Defense response GO:0006952 9 150 475 7,979 Chi-squared test 0.98 Logistic regression 0.88
(b) All level 4          
       Fishers exact Logistic regression
       Fishers exact Bonferroni Logistic regression Bonferroni
Most significant terms          
Protein binding GO:0005515 45 114 1,354 7,100 <0.00001 <0.0006 <0.00001 <0.0006
Morphogenesis GO:0009653 28 131 783 7,671 0.001 0.064 0.001 0.064
Intracellular GO:0005622 93 66 3,845 4,609 0.001 0.064 0.004 0.256
Transcription cofactor activity GO:0003712 10 149 166 8,288 0.002 0.128 <0.00001 <0.0006
RNA polymerase II transcription factor activity GO:0003702 9 150 150 8,304 0.003 0.192 0.001 0.064
Protein serine/threonine phosphatase complex GO:0008287 3 156 19 8,435 0.007 0.448 <0.00001 <0.0006
Helicase activity GO:0004386 6 153 93 8,361 0.01 0.64 0.007 0.448
Structural constituent of epidermis GO:0030280 2 157 7 8,447 0.011 0.704 0.001 0.064
Regulation of physiological process GO:0050791 37 122 1,339 7,115 0.016 1.024 0.014 0.896
Death GO:0016265 11 148 272 8,182 0.02 1.28 0.01 0.64
Pattern specification GO:0007389 2 157 17 8,437 0.047 3.008 0.013 0.832
Antigen binding GO:0003823 2 157 18 8,436 0.052 3.328 0.021 1.344