Table 4 Biological process downregulated in vitro
From: The molecular portrait of in vitro growth by meta-analysis of gene-expression profiles
GO category | Total number of genes | Genes changed | Log10 (p-value) | FDR | ID |
|---|---|---|---|---|---|
Membrane signaling and cell adhesion | Â | Â | Â | Â | Â |
Cell communication | 1088 | 565 | -13.76 | 0.0000 | GO:0007154 |
Signal transduction | 831 | 428 | -8.86 | 0.0000 | GO:0007165 |
Cell surface receptor linked signal transduction | 413 | 232 | -8.66 | 0.0000 | GO:0007166 |
Cell adhesion | 257 | 139 | -4.10 | 0.0000 | GO:0007155 |
Cell-cell signaling | 240 | 132 | -4.38 | 0.0000 | GO:0007267 |
Cell motility | 197 | 105 | -2.91 | 0.0171 | GO:0006928 |
G-protein coupled receptor protein signaling pathway | 175 | 102 | -4.87 | 0.0000 | GO:0007186 |
Enzyme linked receptor protein signaling pathway | 107 | 61 | -2.78 | 0.0231 | GO:0007167 |
Cell-cell adhesion | 87 | 53 | -3.41 | 0.0000 | GO:0016337 |
G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | 35 | 23 | -2.32 | 0.0490 | GO:0007200 |
Extracellular structure organization and biogenesis | 17 | 14 | -3.02 | 0.0029 | GO:0043062 |
Extracellular matrix organization and biogenesis | 16 | 13 | -2.73 | 0.0225 | GO:0030198 |