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Table 1 The initial list of the interactions and proteins represented in each of the existing human protein interaction datasets with total interactions, unique self-interactions and unique non-self interactions

From: Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome

Dataset

Version

Total interactions (number of proteins)

Unique self (A-A) interactions (number of proteins)

Unique (A-B) interactions (number of proteins)

Reactome

08/03/04

12,497 (6,257)

160 (160)

12,336 (807)

BIND

08/03/04

6,212 (5,412)

549 (549)

5,663 (4,762)

HPRD*

04/12/04

12,013 (4,122)

3,028 (3,028)

6,054 (2,747)

Orthology transfer (all)

03/31/04

71,497 (6,257)

373 (373)

71,124 (6,228)

Orthology transfer (core)

03/31/04

11,488 (3,918)

206 (206)

11,282 (3,863)

  1. *Difficult to measure: HPRD records genes by their names, leading occasionally to entries for the same gene under different synonyms. The numbers reported are after mapping to LocusLink.