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Figure 4 | Genome Biology

Figure 4

From: Weighting by heritability for detection of quantitative trait loci with microarray estimates of gene expression

Figure 4

Probe heritability as a predictor of a detectable QTL for a probe set. The figure shows receiver operating characteristic (ROC) curves for prediction of existence of a detectable QTL by either average heritability or maximum heritability among probe-specific data in a probe set. The true-positive fraction on the ordinate is the fraction of probe sets with a significant QTL that are identified as such by selection at a given maximum heritability. The false-positive fraction is the fraction of probe sets without a significant QTL that are selected as having a QTL at the same maximum heritability. Triangle symbols show ROC curve for average heritability; circle symbols show ROC curve for maximum heritability. Circled points are explained in the text

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