Figure 1

Hierarchical cluster analysis of normal tissue specimens. (a) Thumbnail overview of the two-way hierarchical cluster of 115 normal tissue specimens (columns) and 5,592 variably-expressed genes (rows). Mean-centered gene expression ratios are depicted by a log₂ pseudocolor scale (ratio fold-change indicated); gray denotes poorly-measured data. Selected gene-expression clusters are annotated. The dataset represented here is available as Additional data file 2. (b) Enlarged view of the sample dendrogram. Terminal branches for samples are color-coded by tissue type.