Articles selected by Faculty of 1000: microRNA-target interactions; hominid gene control regions; pre-mRNA splicing; gene silencing during pathogenesis; multiple use of microarrays

microRNA-target interactions

A selection of evaluations from Faculty of 1000 covering microRNA-target interactions; hominid gene control regions; pre-mRNA splicing; gene silencing during pathogenesis; multiple use of microarrays.

Architecture of a validated microRNA::target interaction. Vella MC, Reinert K, Slack FJ. Chem Biol 2004, 11:1619-1623.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Vella

Hominid gene control regions

Evidence for widespread degradation of gene control regions in hominid genomes. Keightley PD, Lercher MJ, Eyre-Walker A. PLoS Biol 2005, 3:e42.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Keightley

Pre-mRNA splicing

Small molecule control of pre-mRNA splicing. Graveley BR. RNA 2005, January 20.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Graveley

Gene silencing during pathogenesis

Trypanosoma brucei RNA interference in the mammalian host. Lecordier L, Walgraffe D, Devaux S, Poelvoorde P, Pays E, Vanhamme L. Mol Biochem Parasitol 2005, 142:127-131.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Lecordier

Multiple use of microarrays

Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays. Ronald J, Akey JM, Whittle J, Smith EN, Yvert G, Kruglyak L. Genome Res 2005, 15:284-291.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2005-6-3-314.asp#Ronald