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Table 3 Nested cross-validation results using chromosome 21 genes

From: Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

Pass Number of samples Best inner C-V score (% correct) Number of tied models Outer C-V score (% correct)
Subject 1 3 100.00% (22/22) 116 100.00%
Subject 2 2 100.00% (23/23) 160 100.00%
Subject 3 4 100.00% (21/21) 119 100.00%
Subject 4 4 100.00% (21/21) 142 99.82%
Subject 5 4 100.00% (21/21) 107 100.00%
Subject 6 1 100.00% (24/24) 131 100.00%
Subject 7 4 100.00% (21/21) 247 99.60%
Subject 8 1 100.00% (24/24) 186 100.00%
Subject 9 1 100.00% (24/24) 107 100.00%
Subject 10 1 100.00% (24/24) 212 100.00%
    Accuracy estimate 99.91%
  1. The model space parameters are as follows: Gene selection: ANOVA; Number of genes: 1, 3, 5, ..., 251, 253; Classifier 1: K-Nearest Neighbor (KNN); Number of neighbors (K): 1, 3, 5; Similarity measures: Euclidean distance, Pearson's correlation, Absolute value (also known as 'City block'); Classifier 2: Nearest Centroid, Prior probability: Equal; Classifier 3: Discriminant Analysis, Discriminant functions: Linear, Quadratic, Prior probability: Equal.