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Table 4 Cross-classification of interaction and localization - single projections

From: Ulysses - an application for the projection of molecular interactions across species

  Yeast two-hybrid Complex purification
Interactions Yeast Worm Fly Yeast
  Random BIND Random BIND Random BIND Random BIND
No co-localization 9,493 3 9,475 21 9,454 42 9,314 182
Co-localization 18,656 102 18,614 144 18,628 130 17,411 1,347
Total 28,149 105 28,089 165 28,082 172 26,725 1,529
Success rate 66.28 97.14 66.27 87.27 66.33 75.58 65.15 88.10
p-value   4.3e-09   8.67e-08   0.0111   2e-16
  1. Interactions from model organisms reported in BIND for which both interactors could be mapped to human homologs (HPRD) were evaluated for co-localization. Random interactions generated for HPRD interactors are shown as control datasets.