A computational investigation of kinetoplastid trans-splicing

Table 5 Predictions for chromosome 3

Public annotation	Totals	High confidence	Low confidence	No prediction
Forward strand
Protein function assigned	18	14	4	0
Conserved hypothetical	5	5	0	0
Hypothetical	44	40	4	0
Total	67	59	8	0
Reverse strand
Protein function assigned	7	6	1	0
Conserved hypothetical	2	2	0	0
Hypothetical	22	19	3	0
Total	31	27	4	0

Comparison of predicted splice sites with annotation of chromosome 3 of Leishmania major. A total of 98 genes have been annotated on chromosome 3 of L. major [13]. Of these, the method finds a splice site with a high confidence score in all but 12 instances (88%). A splice site was predicted for every gene annotated on this chromosome.

ISSN: 1474-760X