Table 4 A comparison of candidates for three missing enzymes
From: Computational prediction of human metabolic pathways from the complete human genome
Candidate | Â | P (has-function) | Number of hits | Best E-value | Average rank | Percentage of query aligned |
|---|---|---|---|---|---|---|
Reaction hole: imidazolonepropionase | ||||||
A | ENSG00000139344-MONOMER Functional annotation: UNKNOWN | 0.98 | 28 | 7.0e-69 | 1.0 | 91.9 |
B | ENSG00000119125-MONOMER Functional annotation: Guanine deaminase | 0.00018 | 6 | 3.0e-6 | 3.5 | 37.9 |
Reaction hole: N-acetylglucosamine-6-phosphate deacetylase | ||||||
C | ENSG00000162066-MONOMER Functional annotation:CGI-14 protein | 0.998 | 9 | 1e-110 | 1.0 | 94.6 |
D | ENSG00000119125-MONOMER Functional annotation: Guanine deaminase | 1.0e-5 | 4 | 0.85 | 4.0 | 19.9 |
Reaction hole: aldose 1-epimerase | ||||||
E | ENSG00000143891-MONOMER Functional annotation:AMBIGUOUS | 0.98 | 19 | 3e-74 | 1.58 | 81.9 |
F | ENSG00000117308-MONOMER Functional annotation:UDP-glucose 4-epimerase | 0.93 | 4 | 1e-100 | 1.0 | 58.3 |