Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes

Table 1 Chromosome distribution of HGMD disease gene set

Chromosome	Ensembl gene number	Disease genes	Disease gene percentage
1	2449	115	4.70
2	1706	81	4.75
3	1329	57	4.29
4	1031	39	3.78
5	1138	56	4.92
6	1296	44	3.40
7	1269	51	4.02
8	860	36	4.19
9	1031	45	4.37
10	986	43	4.36
11	1568	77	4.91
12	1207	52	4.31
13	455	25	5.50
14	736	26	3.53
15	797	29	3.64
16	1084	50	4.61
17	1348	68	5.05
18	365	15	4.11
19	1557	55	3.53
20	704	25	3.55
21	192	15	7.81
22	469	25	5.33
X	869	83	9.55

ISSN: 1474-760X