Articles selected by Faculty of 1000: human and chimp methylation patterns; activity-based protein profiling; transcriptional activator targets identified by FRET; onion ESTs; gene organization and mutation rates

Human and chimp methylation patterns

A selection of evaluations from Faculty of 1000 covering human and chimp methylation patterns, activity-based protein profiling, transcriptional activator targets identified by FRET, a set of onion ESTs and gene organization and mutation rates.

Differences in DNA methylation patterns between humans and chimpanzees. Enard W, Fassbender A, ... , Pääbo S, Olek A. Curr Biol 2004, 14:R148-R149.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Enard

Activity-based protein profiling

Mapping enzyme active sites in complex proteomes. Adam GC, Burbaum J, Kozarich JW, Patricelli MP, Cravatt BF. J Am Chem Soc 2004, 126:1363-1368.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Adam

Transcriptional activator targets identified by FRET

In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer. Bhaumik SR, Raha T, Aiello DP, Green MR. Genes Dev 2004, 18:333-343.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Bhaumik

Onion ESTs

A unique set of 11,008 onion expressed sequence tags reveals expressed sequence and genomic differences between the monocot orders Asparagales and Poales. Kuhl JC, Cheung F, Yuan Q, Martin W, Zewdie Y, McCallum J, Catanach A, Rutherford P, Sink KC, Jenderek M, et al. Plant Cell 2004, 16:114-125.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Kuhl

Gene organization and mutation rates

Functional bias and spatial organization of genes in mutational hot and cold regions in the human genome. Chuang JH, Li H. PLoS Biol 2004, 2:E29.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2004-5-4-320.asp#Chuang