Figure 3

SWISS-PROT entries with multiple isoforms amenable to analysis generate more PTC⁺ isoforms. We categorized SWISS-PROT entries by the number of isoforms that are amenable to our analysis, and we then determined how many contained a PTC. Each bar shows the number of PTC⁺ isoforms generated for all SWISS-PROT entries that had the indicated number of isoforms amenable to analysis. Bar components indicate how many entries had a given number of PTC⁺ isoforms. For example, the bar labeled '3' contains data for the 113 SWISS-PROT entries that had 3 isoforms amenable to analysis. 86% of these had no PTC+ isoforms, 10% had one PTC⁺ isoform, and 4% had 2 PTC⁺ isoforms. The bar components outlined in green were SWISS-PROT entries for which all amenable isoforms had a PTC. Entries with multiple isoforms amenable to analysis were more likely to produce at least one PTC⁺ isoform. This study only considered entries with at least two isoforms in the SWISS-PROT database. For many entries only a single isoform is amenable to analysis, however.