Figure 7
From: Model-independent fluxome profiling from 2H and 13C experiments for metabolic variant discrimination
Weights of input variables in the component that is linked to TCA cycle activity, identified by either (a) PCA or (b) ICA from the [U-13C]glucose experiment with ammonium. In (c) and (d), the projections of the mutant data on the component shown in (a) and (b), respectively, were plotted versus the analytically derived fraction of oxaloacetate (OAA) originating from TCA cycle [19]. The correlation coefficients are for linear fits.