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Table 1 Artificial chromosome segregation errors

From: Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes

   Number (%) of chromosome mis-segregation events*
Line Number of cells analyzed Artificial NDJ Lag Host 17 Host X NDJ Lag
17-B12 86 5/208 (2.4) 3 2 3/295 (1.0)   2 1
17-C20 224 91/745 (12.2) 31 60 13/884 (1.5)   9 4
X-4 400 16/866 (1.8) 10 6   25/1,596 (1.6) 20 5
X-5 400 43/1,954 (2.2) 30 13   4/1,588 (0.2) 4 0
  1. *Chromosome segregation errors (either artificial chromosomes or host chromosomes 17 or X) were nondisjunction (NDJ) or anaphase lag (Lag) events. The predominant artificial chromosome segregation error in 17-C20 was due to anaphase lag (66%, n = 91). Data for X-4 and X-5 have been published [14]. Segregation errors that could not be classified (for example, 1:0) were excluded from these analyses.