Articles selected by Faculty of 1000: linkage disequilibrium across the human genome; identifying low abundance proteins; bacterial phylogenetics; trans-acting regulatory variation in yeast; promoter detection in Arabidopsis

Summary

A selection of evaluations from Faculty of 1000 covering the distribution of linkage disequilibrium across the human genome, identifying low abundance and membrane proteins, bacterial phylogenetics, trans-acting regulatory variation in yeast and promoter detection in Arabidopsis.

Linkage disequilibrium across the human genome

Linkage disequilibrium and inference of ancestral recombination in 538 single-nucleotide polymorphism clusters across the human genome. Clark AG, Nielsen R, Signorovitch J, Matise TC, Glanowski S, Heil J, Winn-Deen ES, Holden AL, Lai E. Am J Hum Genet 2003, 73:285-300.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-339.asp#Clark

Identifying low abundance proteins

Unseen proteome: mining below the tip of the iceberg to find low abundance and membrane proteins. Pedersen SK, Harry JL, Sebastian L, Baker J, Traini MD, McCarthy JT, Manoharan A, Wilkins MR, Gooley AA, Righetti PG, et al. J Proteome Res 2003, 2:303-311.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-339.asp#Pedersen

Bacterial phylogenetics

Phylogenetics and the cohesion of bacterial genomes. Daubin V, Moran NA, Ochman H. Science 2003, 301:829-832.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-339.asp#Daubin

Trans-acting regulatory variation in yeast

Trans -acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Yvert G, Brem RB, Whittle J, Akey JM, Foss E, Smith EN, Mackelprang R, Kruglyak L. Nat Genet 2003, Aug 3.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-339.asp#Yvert

Promoter detection in Arabidopsis

Computational approaches to identify promoters and cis -regulatory elements in plant genomes. Rombauts S, Florquin K, Lescot M, Marchal K, Rouzé P, van de Peer Y. Plant Physiol 2003, 132:1162-1176.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-339.asp#Rombauts