Articles selected by Faculty of 1000: archaeal adaptation to cold; human chromosome 7 sequence; comparative protein-structure modeling; new algorithm for sequence alignment; expression profiling human mast cells

Summary

A selection of evaluations from Faculty of 1000 covering genomic analysis of cold-adapted methanogenic archaea, the sequence of human chromosome 7, comparative protein-structure modeling, a new algorithm for multiple sequence alignment and expression profiling human mast cells.

Archaeal adaptation to cold

Mechanisms of thermal adaptation revealed from the genomes of the antarctic archaea Methanogenium frigidum and Methanococcoides burtonii . Saunders NF, Thomas T, Curmi PM, Mattick JS, Kuczek E, Slade R, Davis J, Franzmann PD, Boone D, Rusterholtz K, et al. Genome Res 2003, 13:1580-1588.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-338.asp#Saunders

Human chromosome 7 sequence

The DNA sequence of human chromosome 7. Hillier LW, Fulton RS, Waterston RH, Wilson RK and colleagues. Nature 2003, 424:157-164.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-338.asp#Hillier

Comparative protein-structure modeling

Comparative protein structure modeling by iterative alignment, model building and model assessment. John B, Sali A. Nucleic Acids Res 2003, 31:3982-3892.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-338.asp#John

New algorithm for sequence alignment

SATCHMO: sequence alignment and tree construction using hidden Markov models. Edgar RC, Sjölander K. Bioinformatics 2003, 19:1404-1411.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-338.asp#Edgar

Expression profiling human mast cells

Identification of specific gene expression profile in human mast cells via Toll-like receptor 4 and Fc{epsilon}RI. Okumura S, Kashiwakura JI, Tomita H, Matsumoto K, Nakajima T, Saito H, Okayama Y. Blood 2003, Jul 10.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-9-338.asp#Okumura