Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate

Table 2 Genes with relative differential expression between mouse prostate lobes (p = 0.001 using the Bonferroni correction) with normalized EST numbers

Symbol	Description	UniGene	Species ID	ESTs per lobe
				VP	AP	DLP
Sbp	Spermine binding protein	Mm.46428	6313	3618¹	0¹	2076¹
Spink3	Serine protease inhibitor Kazal type 3	Mm.272	6296	1242¹	0¹	594¹
Vpp1	Ventral prostate predominant 1	Mm.157655	5394	583¹	200^1,2	420²
Ramp2	Receptor (calcitonin) activity modifying protein 2	Mm.218611	4672	42¹	48	157¹
Defβ37	Novel prostate β-defensin 37	-	10164	38	0¹	97¹
A430096B05Rik	RIKEN cDNA A430096B05	Mm.205520	4722	33¹	147¹	78
Pbsn	Probasin	Mm.8034	5239	23¹	1100¹	311¹
Eapa1	Experimental autoimmune prostatitis antigen 1	Mm.221277	5446	18¹	379¹	168¹
Prdx6	Peroxiredoxin 6	Mm.6587	2712	15^1,2	187¹	86²
B2m	β-2 microglobulin	Mm.163	5263	3^1,2	113¹	57²
Svs2	Seminal vesicle protein secretion 2	Mm.143501	1342	2¹	187^1,2	2²
9530003J23Rik	RIKEN cDNA 9530003J23	Mm.118350	5050	2¹	170^1,2	0²
RNAse1	Ribonuclease 1 pancreatic	Mm.3412	4606	0¹	248¹	69¹
Plac8	Onzin (placenta-specific 8)	Mm.34609	5767	0¹	57¹	2
Svs5	Seminal vesicle secretion 5	Mm.140154	506	0¹	31	44¹
-	ESTs similar to acrosomal vesicle protein 1	Mm.118804	2570	0¹	26²	143^1,2

^1,2 Statistically significant gene expression comparisons between lobes are denoted by shared superscripts. VP, ventral prostate; AP, anterior prostate; DLP, dorsolateral prostate.

ISSN: 1474-760X